HLA-B Signal Peptide Polymorphism Influences the Rate of HIV-1 Acquisition but Not Viral Load

Human leukocyte antigen alleles influence the immune response to HIV-1. Signal peptides cleaved from those alleles bind to HLA-E and mediate natural killer cell function. Signal peptides of HLA-A and HLA-C proteins carry methionine (Met) at anchor position 2 (P2); those of HLA-B carry Met or threoni...

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Detalhes bibliográficos
Main Authors: Merino, Aimee M., Song, Wei, He, Dongning, Mulenga, Joseph, Allen, Susan, Hunter, Eric, Tang, Jianming, Kaslow, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3571229/
https://ncbi.nlm.nih.gov/pubmed/22492862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis275
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