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Hypothalamic neuronal toll-like receptor 2 protects against age-induced obesity

Toll-like receptors (TLRs) are traditionally associated with immune-mediated host defense. Here, we ascribe a novel extra-immune, hypothalamic-associated function to TLR2, a TLR-family member known to recognize lipid components, in the protection against obesity. We found that TLR2-deficient mice ex...

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Detalhes bibliográficos
Main Authors: Shechter, Ravid, London, Anat, Kuperman, Yael, Ronen, Ayal, Rolls, Asya, Chen, Alon, Schwartz, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570778/
https://ncbi.nlm.nih.gov/pubmed/23409245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01254
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