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From differences in means between cases and controls to risk stratification: A business plan for biomarker development

Researchers developing biomarkers for early detection can determine the potential for clinical benefit at early stages of development. We provide the theoretical background showing the quantitative connection between biomarker levels in cases and controls and clinically meaningful risk measures and...

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Detalhes bibliográficos
Main Authors: Wentzensen, Nicolas, Wacholder, Sholom
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570740/
https://ncbi.nlm.nih.gov/pubmed/23299199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-12-0196
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