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Perturbations in the gene regulatory pathways controlling mitochondrial energy production in the failing heart

The heart is an omnivore organ that requires constant energy production to match its functional demands. In the adult heart, ATP production occurs mainly through mitochondrial fatty acid and glucose oxidation. The heart must constantly adapt its energy production in response to changes in substrate...

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Main Authors: Aubert, Gregory, Vega, Rick B., Kelly, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570640/
https://ncbi.nlm.nih.gov/pubmed/22964268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.08.015
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