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Chemical Crosslinking and LC/MS Analysis to Determine Protein Domain Orientation: Application to AbrB

To fully understand the modes of action of multi-protein complexes, it is essential to determine their overall global architecture and the specific relationships between domains and subunits. The transcription factor AbrB is a functional homotetramer consisting of two domains per monomer. Obtaining...

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Detalhes bibliográficos
Main Authors: Olson, Andrew L., Liu, Fan, Tucker, Ashley T., Goshe, Michael B., Cavanagh, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570598/
https://ncbi.nlm.nih.gov/pubmed/23313475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2012.12.124
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