Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome

Angelman syndrome (AS) is a neurodevelopment disorder characterized by severe cognitive impairment and a high rate of autism. AS is caused by disrupted neuronal expression of the maternally inherited Ube3A ubiquitin protein ligase, required for the proteasomal degradation of proteins implicated in s...

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Autors principals: Cao, Cong, Rioult-Pedotti, Mengia S., Migani, Paolo, Yu, Crystal J., Tiwari, Rakesh, Parang, Keykavous, Spaller, Mark R., Goebel, Dennis J., Marshall, John
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570550/
https://ncbi.nlm.nih.gov/pubmed/23424281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001478
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