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Impairment of TrkB-PSD-95 Signaling in Angelman Syndrome
Angelman syndrome (AS) is a neurodevelopment disorder characterized by severe cognitive impairment and a high rate of autism. AS is caused by disrupted neuronal expression of the maternally inherited Ube3A ubiquitin protein ligase, required for the proteasomal degradation of proteins implicated in s...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570550/ https://ncbi.nlm.nih.gov/pubmed/23424281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001478 |
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