Glutathione Ethyl Ester Supplementation during Pancreatic Islet Isolation Improves Viability and Transplant Outcomes in a Murine Marginal Islet Mass Model

BACKGROUND: The success of pancreatic islet transplantation still faces many challenges, mainly related to cell damage during islet isolation and early post-transplant. The increased generation of reactive oxygen species (ROS) during islet isolation and the consumption of antioxidant defenses appear...

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Main Authors: Raposo do Amaral, Alexandre S., Pawlick, Rena L., Rodrigues, Erika, Costal, Flavia, Pepper, Andrew, Ferreira Galvão, Flávio H., Correa-Giannella, Maria Lucia, Shapiro, A. M.James
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570543/
https://ncbi.nlm.nih.gov/pubmed/23424628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055288
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