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Generation of Megakaryocytic Progenitors from Human Embryonic Stem Cells in a Feeder- and Serum-Free Medium

BACKGROUND: The production of human platelets from embryonic stem cells in a defined culture system is a prerequisite for the generation of platelets for therapeutic use. As an important step towards this goal, we report the differentiation of human embryonic stem cells (hESCs) towards the megakaryo...

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Autores principales: Pick, Marjorie, Azzola, Lisa, Osborne, Elissa, Stanley, Edouard G., Elefanty, Andrew G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570533/
https://ncbi.nlm.nih.gov/pubmed/23424635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055530
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