Depletion of Aurora A leads to upregulation of FoxO1 to induce cell cycle arrest in hepatocellular carcinoma cells

Aurora A kinase has drawn considerable attention as a therapeutic target for cancer therapy. However, the underlying molecular and cellular mechanisms of the anticancer effects of Aurora A kinase inhibition are still not fully understood. Herein, we show that depletion of Aurora A kinase by RNA inte...

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Autors principals: Lee, Sun-Young, Lee, Gong Rak, Woo, Dong-Hyuk, Park, Neung Hwa, Cha, Hee Jeong, Moon, Yong-Hwan, Han, In-Seob
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570518/
https://ncbi.nlm.nih.gov/pubmed/23255113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22962
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