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p53 restoration kills primitive leukemia cells in vivo and increases survival of leukemic mice
Loss of p53 function is a common feature of human cancers and it is required for differentiated tumor cell maintenance; however, it is not known whether sustained inactivation of the p53 pathway is needed for cancer stem cell persistence. Chronic myeloid leukemia (CML) is caused by a chromosome tran...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3570500/ https://ncbi.nlm.nih.gov/pubmed/23255106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.23031 |
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