P53, MAPK, topoisomerase II alpha and Ki67 immunohistochemical expression and KRAS/BRAF mutation in ovarian serous carcinomas

BACKGROUND: We investigated the immunohistochemical expression of p53, MAPK, topoisomerase II alpha (topoII alpha) and Ki67 in ovarian serous carcinomas (OSCs) along with mutational analysis for KRAS and BRAF. METHODS: Eighty one cases of OSCs were reviewed and examined immunohistochemically using a...

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Autori principali: Sundov, Dinka, Caric, Ana, Mrklic, Ivana, Gugic, Dijana, Capkun, Vesna, Hofman, Irena Drmic, Mise, Branka Petric, Tomic, Snjezana
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570323/
https://ncbi.nlm.nih.gov/pubmed/23388101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-8-21
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