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TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier

BACKGROUND: The TNF ligand family member TWEAK exists as membrane and soluble forms and is involved in the regulation of various human inflammatory pathologies, through binding to its main receptor, Fn14. We have shown that the soluble form of TWEAK has a pro-neuroinflammatory effect in an animal mo...

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Detalhes bibliográficos
Main Authors: Stephan, Delphine, Sbai, Oualid, Wen, Jing, Couraud, Pierre-Olivier, Putterman, Chaim, Khrestchatisky, Michel, Desplat-Jégo, Sophie
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570290/
https://ncbi.nlm.nih.gov/pubmed/23320797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-10-9
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