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Adverse Alterations in Mitochondrial Function Contribute to Type 2 Diabetes Induced Endothelial Dysfunction in Humans

OBJECTIVE: Mitochondrial dysfunction plays a key pathophysiological role in type 2 diabetes (T2DM) related endothelial dysfunction. Data delineating relationships between mitochondrial and endothelial dysfunction in humans with T2DM are lacking. METHODS AND RESULTS: In 122 human subjects, (60 with T...

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Detalhes bibliográficos
Main Authors: Kizhakekuttu, Tinoy J., Wang, Jingli, Dharmashankar, Kodlipet, Ying, Rong, Gutterman, David D., Vita, Joseph A., Widlansky, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570053/
https://ncbi.nlm.nih.gov/pubmed/22879582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.256024
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