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Autophagy, mitochondria and 3-nitropropionic acid joined in the same model

Huntington's disease (HD) is a neurodegenerative disorder caused by a mutation in the gene encoding the huntingtin protein. Although the precise mechanism by which neuronal degeneration occurs is still unclear, several elements are important to its development: (1) altered gene expression and p...

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Bibliographic Details
Main Authors: González-Polo, Rosa A, Bravo-San Pedro, José M, Gómez-Sánchez, Rubén, Pizarro-Estrella, Elisa, Niso-Santano, Mireia, Fuentes, José M
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3570003/
https://ncbi.nlm.nih.gov/pubmed/22946678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2012.02203.x
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