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Adiposity Blunts the Positive Relationship of Thyrotropin with Proprotein Convertase Subtilisin-Kexin Type 9 Levels in Euthyroid Subjects

BACKGROUND: Effects of thyroid function status on lipoprotein metabolism may extend into the euthyroid range. Low-density lipoprotein (LDL) metabolism is governed by proprotein convertase subtilisin-kexin type 9 (PCSK9), which down-regulates LDL receptor expression, resulting in higher LDL cholester...

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Autors principals: Kwakernaak, Arjan J., Lambert, Gilles, Muller Kobold, Anneke C., Dullaart, Robin P.F.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569926/
https://ncbi.nlm.nih.gov/pubmed/23106476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/thy.2012.0434
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