Polymorphism in the Plasmodium falciparum erythrocyte-binding ligand JESEBL/EBA-181 alters its receptor specificity

The malaria parasite lives within erythrocytes and depends on the binding of parasite ligands to host cell surface receptors for invasion. The most virulent human malaria parasite, Plasmodium falciparum, uses multiple ligands, including EBA-175, BAEBL, and JESEBL of the Duffy-binding-like (DBL) fami...

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Bibliographic Details
Main Authors: Mayer, D. C. Ghislaine, Mu, Jian-Bing, Kaneko, Osamu, Duan, Junhui, Su, Xin-zhuan, Miller, Louis H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC356982/
https://ncbi.nlm.nih.gov/pubmed/14983041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307318101
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