Zinc-α2-glycoprotein, a lipid mobilizing factor, is expressed in adipocytes and is up-regulated in mice with cancer cachexia

Zinc-α2-glycoprotein (ZAG), a 43-kDa protein, is overexpressed in certain human malignant tumors and acts as a lipid-mobilizing factor to stimulate lipolysis in adipocytes leading to cachexia in mice implanted with ZAG-producing tumors. Because white adipose tissue (WAT) is an endocrine organ secret...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Bing, Chen, Bao, Yi, Jenkins, John, Sanders, Paul, Manieri, Monia, Cinti, Saverio, Tisdale, Michael J., Trayhurn, Paul
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356979/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14983038/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308647100
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