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An anti-CD45RO immunotoxin kills HIV-latently infected cells from individuals on HAART with little effect on CD8 memory
CD4(+) CD45RO(+) T cells are the major latent viral reservoir in HIV-infected individuals and hence a major obstacle in curing the disease. An anti-CD45RO immunotoxin (IT) can decrease the number of both productively and latently infected CD4(+) T cells obtained from HIV-infected individuals with de...
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| Autores principales: | , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2004
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC356978/ https://ncbi.nlm.nih.gov/pubmed/14983037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308381100 |
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