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Adiponectin-induced antiangiogenesis and antitumor activity involve caspase-mediated endothelial cell apoptosis

Obesity is a risk factor for the development of many severe human diseases such as cardiovascular disorders, diabetes, and cancer, which are tightly linked to angiogenesis. The adipose tissue produces several growth factors/hormones including leptin, tumor necrosis factor α, and adiponectin. It has...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Bråkenhielm, Ebba, Veitonmäki, Niina, Cao, Renhai, Kihara, Shinji, Matsuzawa, Yuji, Zhivotovsky, Boris, Funahashi, Tohru, Cao, Yihai
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356975/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14983034/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308671100
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