Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

Histone deacetylases (HDACs) are currently being discussed as promising therapeutic targets to treat neurodegenerative diseases. However, the role of specific HDACs in cognition and neurodegeneration remains poorly understood. Here, we investigate the function of HDAC6, a class II member of the HDAC...

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Bibliografske podrobnosti
Main Authors: Govindarajan, Nambirajan, Rao, Pooja, Burkhardt, Susanne, Sananbenesi, Farahnaz, Schlüter, Oliver M, Bradke, Frank, Lu, Jianrong, Fischer, André
Format: Artigo
Jezik:Inglês
Izdano: WILEY-VCH Verlag 2013
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569653/
https://ncbi.nlm.nih.gov/pubmed/23184605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201923
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