Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

Histone deacetylases (HDACs) are currently being discussed as promising therapeutic targets to treat neurodegenerative diseases. However, the role of specific HDACs in cognition and neurodegeneration remains poorly understood. Here, we investigate the function of HDAC6, a class II member of the HDAC...

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Autores principales: Govindarajan, Nambirajan, Rao, Pooja, Burkhardt, Susanne, Sananbenesi, Farahnaz, Schlüter, Oliver M, Bradke, Frank, Lu, Jianrong, Fischer, André
Formato: Artigo
Lenguaje:Inglês
Publicado: WILEY-VCH Verlag 2013
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569653/
https://ncbi.nlm.nih.gov/pubmed/23184605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201923
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