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Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

Histone deacetylases (HDACs) are currently being discussed as promising therapeutic targets to treat neurodegenerative diseases. However, the role of specific HDACs in cognition and neurodegeneration remains poorly understood. Here, we investigate the function of HDAC6, a class II member of the HDAC...

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Hlavní autoři: Govindarajan, Nambirajan, Rao, Pooja, Burkhardt, Susanne, Sananbenesi, Farahnaz, Schlüter, Oliver M, Bradke, Frank, Lu, Jianrong, Fischer, André
Médium: Artigo
Jazyk:Inglês
Vydáno: WILEY-VCH Verlag 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569653/
https://ncbi.nlm.nih.gov/pubmed/23184605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201923
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