Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

Histone deacetylases (HDACs) are currently being discussed as promising therapeutic targets to treat neurodegenerative diseases. However, the role of specific HDACs in cognition and neurodegeneration remains poorly understood. Here, we investigate the function of HDAC6, a class II member of the HDAC...

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Autors principals: Govindarajan, Nambirajan, Rao, Pooja, Burkhardt, Susanne, Sananbenesi, Farahnaz, Schlüter, Oliver M, Bradke, Frank, Lu, Jianrong, Fischer, André
Format: Artigo
Idioma:Inglês
Publicat: WILEY-VCH Verlag 2013
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569653/
https://ncbi.nlm.nih.gov/pubmed/23184605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201923
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