Strategy for the creation of clinical grade hESC line banks that HLA-match a target population

Here, we describe a pre-derivation embryo haplotyping strategy that we developed in order to maximize the efficiency and minimize the costs of establishing banks of clinical grade hESC lines in which human leukocyte antigen (HLA) haplotypes match a significant proportion of the population. Using who...

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Detalhes bibliográficos
Main Authors: Jacquet, Laureen, Stephenson, Emma, Collins, Robert, Patel, Heema, Trussler, Jane, Al-Bedaery, Roaa, Renwick, Pamela, Ogilvie, Caroline, Vaughan, Robert, Ilic, Dusko
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569650/
https://ncbi.nlm.nih.gov/pubmed/23161805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201973
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