Skin-draining lymph node priming is sufficient to induce sterile immunity against pre-erythrocytic malaria

The Plasmodium-infected hepatocyte has been considered necessary to prime the immune responses leading to sterile protection after vaccination with attenuated sporozoites. However, it has recently been demonstrated that priming also occurs in the skin. We wished to establish if sterile protection co...

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Main Authors: Obeid, Michel, Franetich, Jean-François, Lorthiois, Audrey, Gego, Audrey, Grüner, Anne Charlotte, Tefit, Maurel, Boucheix, Claude, Snounou, Georges, Mazier, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: WILEY-VCH Verlag 2013
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569641/
https://ncbi.nlm.nih.gov/pubmed/23255300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201677
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