The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes

Immunoglobulins, antigens and complement can assemble to form immune complexes (IC). ICs can be detrimental as they propagate inflammation in autoimmune diseases. Like ICs, submicron extracellular vesicles termed microparticles (MP) are present in the synovial fluid from patients affected with autoi...

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Détails bibliographiques
Auteurs principaux: Cloutier, Nathalie, Tan, Sisareuth, Boudreau, Luc H, Cramb, Catriona, Subbaiah, Roopashree, Lahey, Lauren, Albert, Alexandra, Shnayder, Ruslan, Gobezie, Reuben, Nigrovic, Peter A, Farndale, Richard W, Robinson, William H, Brisson, Alain, Lee, David M, Boilard, Eric
Format: Artigo
Langue:Inglês
Publié: WILEY-VCH Verlag 2013
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569640/
https://ncbi.nlm.nih.gov/pubmed/23165896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201846
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