The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes

Immunoglobulins, antigens and complement can assemble to form immune complexes (IC). ICs can be detrimental as they propagate inflammation in autoimmune diseases. Like ICs, submicron extracellular vesicles termed microparticles (MP) are present in the synovial fluid from patients affected with autoi...

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Main Authors: Cloutier, Nathalie, Tan, Sisareuth, Boudreau, Luc H, Cramb, Catriona, Subbaiah, Roopashree, Lahey, Lauren, Albert, Alexandra, Shnayder, Ruslan, Gobezie, Reuben, Nigrovic, Peter A, Farndale, Richard W, Robinson, William H, Brisson, Alain, Lee, David M, Boilard, Eric
Format: Artigo
Language:Inglês
Published: WILEY-VCH Verlag 2013
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569640/
https://ncbi.nlm.nih.gov/pubmed/23165896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201846
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