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Blockade of Insect Odorant Receptor Currents by Amiloride Derivatives

Insect odorant receptors (ORs) function as heteromeric odorant-gated ion channels consisting of a conserved coreceptor, Orco, and an odorant-sensitive tuning subunit. Although some OR modulators have been identified, an extended library of pharmacological tools is currently lacking and would aid in...

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Detalhes bibliográficos
Main Authors: Pask, Gregory M., Bobkov, Yuriy V., Corey, Elizabeth A., Ache, Barry W., Zwiebel, Laurence J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569625/
https://ncbi.nlm.nih.gov/pubmed/23292750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chemse/bjs100
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