Endotoxin induces proliferation of NSCLC in vitro and in vivo: role of COX-2 and EGFR activation

Lung cancer is frequently complicated by pulmonary infections which may impair prognosis of this disease. Therefore, we investigated the effect of bacterial lipopolysaccharides (LPS) on tumor proliferation in vitro in the non-small cell lung cancer (NSCLC) cell line A549, ex vivo in a tissue culture...

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Detalhes bibliográficos
Main Authors: Hattar, Katja, Savai, Rajkumar, Subtil, Florentine S. B., Wilhelm, Jochen, Schmall, Anja, Lang, Dagmar S., Goldmann, Torsten, Eul, Bastian, Dahlem, Gabriele, Fink, Ludger, Schermuly, Ralph-Theo, Banat, Gamal-Andre, Sibelius, Ulf, Grimminger, Friedrich, Vollmer, Ekkehard, Seeger, Werner, Grandel, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569588/
https://ncbi.nlm.nih.gov/pubmed/22923191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-012-1341-2
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