Activation of integrin β-subunit I-like domains by one-turn C-terminal α-helix deletions

Integrins contain two structurally homologous but distantly related domains: an I-like domain that is present in all β-subunits and an I domain that is present in some α-subunits. Atomic resolution and mutagenesis studies of α I domains demonstrate a C-terminal, axial displacement of the α7-helix th...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Yang, Wei, Shimaoka, Motomu, Chen, JianFeng, Springer, Timothy A.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 2004
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356951/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14983010/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307291101
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