Differential recruitment of nuclear receptor coactivators may determine alternative RNA splice site choice in target genes

The biological consequences of steroid hormone-mediated transcriptional activation of target genes might be difficult to predict because alternative splicing of a single neosynthesized precursor RNA can result in production of different protein isoforms with opposite biological activities. Therefore...

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Bibliographic Details
Main Authors: Auboeuf, Didier, Dowhan, Dennis H., Kang, Yun Kyoung, Larkin, Kimberly, Lee, Jae Woon, Berget, Susan M., O'Malley, Bert W.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC356940/
https://ncbi.nlm.nih.gov/pubmed/14982999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308133100
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