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Engineering Escherichia coli for efficient conversion of glucose to pyruvate

Escherichia coli TC44, a derivative of W3110, was engineered for the production of pyruvate from glucose by combining mutations to minimize ATP yield, cell growth, and CO(2) production (ΔatpFH ΔadhE ΔsucA) with mutations that eliminate acetate production [poxB::FRT (FLP recognition target) ΔackA] an...

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Bibliographic Details
Main Authors: Causey, T. B., Shanmugam, K. T., Yomano, L. P., Ingram, L. O.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC356934/
https://ncbi.nlm.nih.gov/pubmed/14982993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308171100
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