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NC1900, an Arginine Vasopressin Analogue, Fails to Reduce Brain Edema and Improve Neurobehavioral Deficits in an Intracerebral Hemorrhagic Stroke Mice Model

OBJECTIVE: There is mounting evidence suggesting that arginine vasopressin via its V1a receptor interaction is involved in the regulation of the brain water channel, aquaporin-4 (AQP4). The role of AQP4 in brain edema resolution has been thoroughly investigated in knock-out animal studies, which sho...

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Main Authors: Manaenko, Anatol, Lekic, Tim, Tang, Jiping, Zhang, John H.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569077/
https://ncbi.nlm.nih.gov/pubmed/21725748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-7091-0693-8_26
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