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Kinetic and Mechanistic Characterization and Versatile Catalytic Properties of Mammalian Glutaredoxin 2: Implications for Intracellular Roles

Glutaredoxin (Grx)-catalyzed deglutathionylation of protein–glutathione mixed disulfides (protein-SSG) serves important roles in redox homeostasis and signal transduction, regulating diverse physiological and pathophysiological events. Mammalian cells have two Grx isoforms: Grx1, localized to the cy...

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Detalhes bibliográficos
Main Authors: Gallogly, Molly M., Starke, David W., Leonberg, Amanda K., Ospina, Susan M. English, Mieyal, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3569056/
https://ncbi.nlm.nih.gov/pubmed/18816065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800966v
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