Comparison of Conventional Bacteriology with Nucleic Acid Amplification (Amplified Mycobacterium Direct Test) for Diagnosis of Tuberculous Meningitis before and after Inception of Antituberculosis Chemotherapy

The role of nucleic acid amplification techniques in the rapid diagnosis of tuberculous meningitis remains uncertain. We compared the performance of Ziehl-Neelsen (ZN) staining, the Gen-Probe amplified Mycobacterium tuberculosis direct test (MTD), and culture with 341 cerebrospinal fluid specimens f...

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Bibliographic Details
Main Authors: Thwaites, Guy E., Caws, Maxine, Chau, Tran Thi Hong, Dung, Nguyen Thi, Campbell, James I., Phu, Nguyen Hoan, Hien, Tran Tinh, White, Nicholas J., Farrar, Jeremy J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2004
Subjects:
Mycobacteriology and Aerobic Actinomycetes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC356903/
https://ncbi.nlm.nih.gov/pubmed/15004044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.3.996-1002.2004
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