Potential Impact of Adding Genetic Markers to Clinical Parameters in Predicting Prostate Biopsy Outcomes in Men Following an Initial Negative Biopsy: Findings from the REDUCE Trial

BACKGROUND: Several germline single nucleotide polymorphisms (SNPs) have been consistently associated with prostate cancer (PCa) risk. OBJECTIVE: To determine whether there is an improvement in PCa risk prediction by adding these SNPs to existing predictors of PCa. DESIGN, SETTING, AND PARTICIPANTS:...

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Detalhes bibliográficos
Main Authors: Kader, A. Karim, Sun, Jielin, Reck, Brian H., Newcombe, Paul J., Kim, Seong-Tae, Hsu, Fang-Chi, D’Agostino, Ralph B., Tao, Sha, Zhang, Zheng, Turner, Aubrey R., Platek, Greg T., Spraggs, Colin F., Whittaker, John C., Lane, Brian R., Isaacs, William B., Meyers, Deborah A., Bleecker, Eugene R., Torti, Frank M., Trent, Jeffery M., McConnell, John D., Zheng, S. Lilly, Condreay, Lynn D., Rittmaster, Roger S., Xu, Jianfeng
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568765/
https://ncbi.nlm.nih.gov/pubmed/22652152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2012.05.006
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