Interferon release does not add discriminatory value to smear-negative HIV–tuberculosis algorithms

Clinical algorithms for evaluating HIV-infected individuals for tuberculosis (TB) prior to isoniazid preventive therapy (IPT) perform poorly, and interferon-γ release assays (IGRAs) have moderate accuracy for active TB. It is unclear whether, when used as adjunct tests, IGRAs add any clinical discri...

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Autori principali: Rangaka, M.X., Gideon, H.P., Wilkinson, K.A., Pai, M., Mwansa-Kambafwile, J., Maartens, G., Glynn, J.R., Boulle, A., Fielding, K., Goliath, R., Titus, R., Mathee, S., Wilkinson, R.J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568692/
https://ncbi.nlm.nih.gov/pubmed/21719487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00058911
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