Identification of a Mycobacterium tuberculosis Strain with Stable, Low-Level Resistance to Isoniazid

We have identified a potential quality control strain of Mycobacterium tuberculosis to monitor isoniazid susceptibility testing. This strain (strain A) has a stable phenotypic low-level resistance to isoniazid, has a mutation of C (−15) → T in the inhA promoter region, and gave consistent susceptibi...

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Detalhes bibliográficos
Main Authors: Madison, Bereneice M., Siddiqi, Salman H., Heifets, Leonid, Gross, Wendy, Higgins, Mike, Warren, Nancy, Thompson, Anthony, Morlock, Glenn, Ridderhof, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Mycobacteriology and Aerobic Actinomycetes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356860/
https://ncbi.nlm.nih.gov/pubmed/15004099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.3.1294-1295.2004
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