JNK inhibition reduces apoptosis and neovascularization in a murine model of age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of registered blindness among the elderly and affects over 30 million people worldwide. It is well established that oxidative stress, inflammation, and apoptosis play critical roles in pathogenesis of AMD. In advanced wet AMD, although, mos...

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Detalhes bibliográficos
Main Authors: Du, Hongjun, Sun, Xufang, Guma, Monica, Luo, Jing, Ouyang, Hong, Zhang, Xiaohui, Zeng, Jing, Quach, John, Nguyen, Duy H., Shaw, Peter X., Karin, Michael, Zhang, Kang
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568328/
https://ncbi.nlm.nih.gov/pubmed/23341606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1221729110
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