Human Monoclonal Antibody Fragment Specific for Glycoprotein G in Herpes Simplex Virus Type 2 with Applications for Serotype-Specific Diagnosis

A combinatorial library was used to select a human monoclonal antibody fragment (Fab) with high affinity for G glycoprotein in herpes simplex virus type 2 (HSV-2). Tests with 112 clinical specimens demonstrated successful discrimination between HSV-2 and HSV-1, showing the potential of Fab as a low-...

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Detalhes bibliográficos
Main Authors: Bugli, Francesca, Manzara, Stefania, Torelli, Riccardo, Graffeo, Rosalia, Santangelo, Rosaria, Cattani, Paola, Fadda, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC356824/
https://ncbi.nlm.nih.gov/pubmed/15004085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.42.3.1250-1253.2004
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