Human Monoclonal Antibody Fragment Specific for Glycoprotein G in Herpes Simplex Virus Type 2 with Applications for Serotype-Specific Diagnosis

A combinatorial library was used to select a human monoclonal antibody fragment (Fab) with high affinity for G glycoprotein in herpes simplex virus type 2 (HSV-2). Tests with 112 clinical specimens demonstrated successful discrimination between HSV-2 and HSV-1, showing the potential of Fab as a low-...

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Publicat a:J Clin Microbiol
Autors principals: Bugli, Francesca, Manzara, Stefania, Torelli, Riccardo, Graffeo, Rosalia, Santangelo, Rosaria, Cattani, Paola, Fadda, Giovanni
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2004
Matèries:
Virology
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC356824/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15004085/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JCM.42.3.1250-1253.2004
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