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The role of mesothelin in tumor progression and targeted therapy

Mesothelin, a glycosylphosphatidylinositol (GPI) anchored cell surface protein, is a potential target for antibody-based cancer therapy due to its high expression in mesothelioma, ovarian cancer, pancreatic cancer, cholangiocarcinoma and other cancers. The SS1P immunotoxin and MORAb-009 (amatuximab)...

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Hlavní autoři: Tang, Zhewei, Qian, Min, Ho, Mitchell
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568227/
https://ncbi.nlm.nih.gov/pubmed/22721387
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