Aberrant Glycogen Synthase Kinase 3β Is Involved in Pancreatic Cancer Cell Invasion and Resistance to Therapy

BACKGROUND AND PURPOSE: The major obstacles to treatment of pancreatic cancer are the highly invasive capacity and resistance to chemo- and radiotherapy. Glycogen synthase kinase 3β (GSK3β) regulates multiple cellular pathways and is implicated in various diseases including cancer. Here we investiga...

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Detalhes bibliográficos
Main Authors: Kitano, Ayako, Shimasaki, Takeo, Chikano, Yuri, Nakada, Mitsutoshi, Hirose, Mayumi, Higashi, Tomomi, Ishigaki, Yasuhito, Endo, Yoshio, Takino, Takahisa, Sato, Hiroshi, Sai, Yoshimichi, Miyamoto, Ken-ichi, Motoo, Yoshiharu, Kawakami, Kazuyuki, Minamoto, Toshinari
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568118/
https://ncbi.nlm.nih.gov/pubmed/23408967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055289
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