EspO1-2 Regulates EspM2-Mediated RhoA Activity to Stabilize Formation of Focal Adhesions in Enterohemorrhagic Escherichia coli-Infected Host Cells

Enterohemorrhagic Escherichia coli (EHEC) Sakai strain encodes two homologous type III effectors, EspO1-1 and EspO1-2. These EspO1s have amino acid sequence homology with Shigella OspE, which targets integrin-linked kinase to stabilize formation of focal adhesions (FAs). Like OspE, EspO1-1 was local...

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Autors principals: Morita-Ishihara, Tomoko, Miura, Masashi, Iyoda, Sunao, Izumiya, Hidemasa, Watanabe, Haruo, Ohnishi, Makoto, Terajima, Jun
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568036/
https://ncbi.nlm.nih.gov/pubmed/23409096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0055960
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