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ROCS: a Reproducibility Index and Confidence Score for Interaction Proteomics Studies

BACKGROUND: Affinity-Purification Mass-Spectrometry (AP-MS) provides a powerful means of identifying protein complexes and interactions. Several important challenges exist in interpreting the results of AP-MS experiments. First, the reproducibility of AP-MS experimental replicates can be low, due bo...

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Autori principali: Dazard, Jean-Eudes, Saha, Sudipto, Ewing, Rob M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3568013/
https://ncbi.nlm.nih.gov/pubmed/22682516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-128
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