Hypoxia Modulates A431 Cellular Pathways Association to Tumor Radioresistance and Enhanced Migration Revealed by Comprehensive Proteomic and Functional Studies

Tumor hypoxia induces cancer cell angiogenesis, invasiveness, treatment resistance, and contributes to poor clinical outcome. However, the molecular mechanism by which tumor hypoxia exerts a coordinated effect on different molecular pathways to enhance tumor growth and survival and lead to poor clin...

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Main Authors: Ren, Yan, Hao, Piliang, Dutta, Bamaprasad, Cheow, Esther Sok Hwee, Sim, Kae Hwan, Gan, Chee Sian, Lim, Sai Kiang, Sze, Siu Kwan
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2013
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567868/
https://ncbi.nlm.nih.gov/pubmed/23204318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M112.018325
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