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Chronic lymphocytic leukemia: A tale of one or two signals?

The significant correlation between disease aggressiveness and the gene and protein structures of the B-cell receptors (BCRs) expressed on chronic lymphocytic leukemia (CLL) cells, together with the evidence for chronic activation of the BCR pathway, have led to the hypothesis that this leukemia ini...

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Autors principals: Chiorazzi, Nicholas, Efremov, Dimitar G
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567819/
https://ncbi.nlm.nih.gov/pubmed/23147791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2012.152
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