Assessment of Complement C4 Gene Copy Number Using the Paralog Ratio Test

The complement C4 locus is in the class III region of the MHC, and exhibits copy number variation. Complement C4 null alleles have shown association with a number of diseases including systemic lupus erythematosus (SLE). However, most studies to date have used protein immunophenotyping and not direc...

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Main Authors: Fernando, Michelle M.A., Boteva, Lora, Morris, David L., Zhou, Bi, Wu, Yee Ling, Lokki, Marja-Liisa, Yu, Chack Yung, Rioux, John D., Hollox, Edward J., Vyse, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567757/
https://ncbi.nlm.nih.gov/pubmed/20506482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.21259
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