Mesencephalic Astrocyte-derived Neurotrophic Factor (MANF) Secretion and Cell Surface Binding Are Modulated by KDEL Receptors

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER) stress-responsive protein with neuroprotective effects in animal models of neurodegeneration, but the underlying mechanism is not understood. We constructed a set of lentiviral vectors that contain or lack th...

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Bibliographische Detailangaben
Hauptverfasser: Henderson, Mark J., Richie, Christopher T., Airavaara, Mikko, Wang, Yun, Harvey, Brandon K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Cell Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567670/
https://ncbi.nlm.nih.gov/pubmed/23255601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.400648
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