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Peroxisome Proliferator-activated Receptor γ Agonists Induce Cell Cycle Arrest through Transcriptional Regulation of Krüppel-like Factor 4 (KLF4)

Peroxisome proliferator-activated receptor γ (PPARγ), a subgroup of ligand-activated nuclear receptors, plays critical roles in cell cycle regulation, differentiation, apoptosis, and invasion. PPARγ is involved in tumorigenesis and is a potent target for cancer therapy. PPARγ transactivation of KLF4...

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Detalles Bibliográficos
Main Authors: Li, Sheng, Zhou, Qibing, He, Huan, Zhao, Yahui, Liu, Zhihua
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567659/
https://ncbi.nlm.nih.gov/pubmed/23275339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.317487
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