Several Phenylalanine-Glycine Motives in the Nucleoporin Nup214 Are Essential for Binding of the Nuclear Export Receptor CRM1

Nucleoporins containing phenylalanine glycine (FG) repeats play an important role in nucleocytoplasmic transport as they bind to transport receptors and mediate translocation of transport complexes across the nuclear pore complex (NPC). Nup214/CAN, a nucleoporin that is found at the cytoplasmic side...

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Bibliographic Details
Main Authors: Roloff, Stephanie, Spillner, Christiane, Kehlenbach, Ralph H.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2013
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567648/
https://ncbi.nlm.nih.gov/pubmed/23264634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.433243
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