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Chtop is a component of the dynamic TREX mRNA export complex

The TREX complex couples nuclear pre-mRNA processing with mRNA export and contains multiple protein components, including Uap56, Alyref, Cip29 and the multi-subunit THO complex. Here, we have identified Chtop as a novel TREX component. We show that both Chtop and Alyref activate the ATPase and RNA h...

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Detalhes bibliográficos
Main Authors: Chang, Chung-Te, Hautbergue, Guillaume M, Walsh, Matthew J, Viphakone, Nicolas, van Dijk, Thamar B, Philipsen, Sjaak, Wilson, Stuart A
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3567497/
https://ncbi.nlm.nih.gov/pubmed/23299939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.342
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