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Chtop is a component of the dynamic TREX mRNA export complex
The TREX complex couples nuclear pre-mRNA processing with mRNA export and contains multiple protein components, including Uap56, Alyref, Cip29 and the multi-subunit THO complex. Here, we have identified Chtop as a novel TREX component. We show that both Chtop and Alyref activate the ATPase and RNA h...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
European Molecular Biology Organization
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3567497/ https://ncbi.nlm.nih.gov/pubmed/23299939 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.342 |
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